Prof. Dr. Daniel Huster (Institute of Medical Physics and Biophysics, University of Leipzig)
„Small Molecules Modulate the Properties of Cholesterol-Containing Membranes“
Cholesterol has been known to play a decisive role in biological membranes. In the talk, I shall be discussing specific molecular properties of cholesterol with regard to its specific function in the maintenance of the membrane’s barrier function. Especially, the length of cholesterol’s side chain will be addressed . I will continue presenting data on the specific interaction of cholesterol with lipids in mixed membranes  and raft mixtures [3,4]. Next, I will be presenting unpublished data on the modulation of the lateral organization of raft mixtures by small neurotransmitters. Finally, an example of the modulation of the structural dynamics of a membrane protein by membrane cholesterol will be given. In our group, we use solid-state NMR techniques to study membranes of mixed complexity on a molecular level.
Date: Tuesday, 10th December 2019, 5.00 pm (s.t.)
Venue: Seminar Room Cell Biology (00.581), Department Biology, Building B1, Floor 00, Staudtstraße 5, 91058 Erlangen